Cedars-Sinai
Biostatistics Fall Quarter - Presentations, Assignments and other material
Instructor: Jeff Gornbein DrPH gornbein@g.ucla.edu
Home phone: 310-392-7381 office: 310-825-4193
Class
topics schedule & texts (updated) Handy EXCEL functions Gaussian
(normal) table
Suggested texts: Petrie and Sabin (P&S) Medical Statistics at a Glance 4th
ed, Wiley-Blackwell Pub 2020, Motulsky H, Intuitive Biostatistics, 4th ed,
Oxford Univ Press 2018
Link to class
Zoom session: https://uclahs.zoom.us/j/3680482651
Meeting ID: 368 048
2651
Class
presentation slides by topic- will be updated
2. Descriptive stats-survival
& binary data, Sensitivity, Specificity and ROC
3.
Probability theory & distributions: Normal, binomial, Poisson Bayes rule
4. Confidence intervals
& hypothesis testing, p values
Paper on the misinterpretation of p values
(Lytsy-2022)
5.
Sample size for precision & power, multiple hypothesis testing
6.
Analysis of variance (ANOVA)
7. Chi square and F
tests overall tests
8b. Multiple regression
brief intro to linear, logistic, Poisson & Cox regression
9C. Propensity scores & logistic regression
10. Survival and Cox regression
12. Stat reporting tips for stats in publications
Class notes (backup, less up to date):
Semi
serious stat survey a screening test (not for a grade-do not need to
hand in)
Assignments: Due dates
will be extended if material has not yet been covered
Send assignment
response in MS Word format to gornbein@g.ucla.edu
Assignment 1
due 11 Sept, 2023 Peters article Staudmauer
article
Assignment 2
due 25 Sept, 2023
Assignment 3
due 16 Oct, 2023 Julian article
Assignment 4
due 6 Nov, 2023
sample
size/power table for comparing two means
sample
size/power table for comparing two proportions
Assignment 5 due 27 Nov, 2023 Atkins
vs Zone article
Assignment 6 optional
Testosterone article
Final presentation instructions
Other papers: Stratton & Neil -how to ensure
paper is rejected
Ioannidis why
published results can be false
Online
calculators
Normal
distribution applet / calculator
Power
for Comparing two means (comparing mean difference to zero)
Download for free Gpower sample size/power software
University of Dusseldorf (must download and install)
Notes for JMP
sessions
Lab
1 introduction to JMP data for BMI example depression data (JMP
format)
Excel demos and model calculators
Normal distribution area
calculator
Chi square area (p value) calculator
Poisson distribution calculator
t test for
means and Z test for proportions-calculator
power calculation demo t test
sample size calculation
for comparing two means t test
proportion comparison Z test
calculator
chi-square
test calculation demo
Logistic
regression diabetes complication risk calculator
Datasets
in EXCEL (some in JMP) used to illustrate some material:
Birth weight
(BWEIGHT) data dictionary for BWEIGHT
Svol (semen volume used in regression)
Clond TBI data (used
in ANOVA)
PCO data in JMP format used for regression
Depression
(CESD) data in JMP format-used for regression
Chung-Prati cancer survival data in JMP format
Links to Recorded Lectures (Zoom)
there is a lag before recorded lectures are posted
Click on link
29
Aug 2023 Introductions, Confounding and bias
12
Sept 2023 Descriptive statistics continuous data
19
Sept 2023 Binary descriptive statistics, Sensitivity, Specificity, ROC
26
Sept 2023 - Gaussian (normal)
distribution
26 Sept 2023 Introduction to JMP
(optional)
3
Oct 2023 Probability, Bayes Theorem, sampling distributions, confidence
intervals
10
Oct, 2023 - Hypothesis testing, non inferiority testing
17
Oct, 2023 - Power and sample size
24
Oct, 2023 multiple hypothesis testing, FWER, FDR (JMP ROC is second recording)
31
Oct, 2023 comparing means analysis of variance (ANOVA)
7
Nov, 2023 multi way analysis of variance
14
Nov, 2023 chi square and McNemar test,
simple linear regression
21
Nov, 2023 linear regression limitations, linearity & splines
28
Nov, 2023 multiple regression overview, multiple linear regression interaction
